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The final results illustrated the RGD motif enhanced GHK adsorption and accumulation in the skin, which contributed for the community peptide density as well as the bioactivities of GHK. Listed here, although sOtx2-GHK exhibited improved cell adhesion, its skin adsorption is weaker than RGD-GHK. One reason for the contradictory effects of RGD-GHK b
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